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This registration process only needs to be completed once Use of cosmic select your organisation type organisation type select your intended use of cosmic intended use of cosmic Please contact us via cosmic@sanger.ac.uk if you encounter any issues.

Cosmic mutational signatures is a catalogue of curated reference mutational signatures This is the cosmic downloads page Curation covers aetiology, acceptance criteria, tissue distribution and other genomic features of each mutational signature

Downloadable signature profiles and other data are freely available.

The aim of cosmic mutation actionability in precision oncology product (actionability) is to indicate the availability of drugs that target mutations in cancer and track the progress of clinical studies towards making new drugs available. Cosmic, the catalogue of somatic mutations in cancer, is the world's largest and most comprehensive resource for exploring the impact of somatic mutations in human cancer.

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