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Tenecteplase (tnk) can help dissolve blood clots to treat acute ischemic stroke Our network has adopted tenecteplase, or tnk, for ischemic stroke patients. Learn about how it works, when doctors administer it, and more.
Tenecteplase is an enzyme that, when present in blood in pharmacologic concentrations, remains active under in vitro conditions It enhances the conversion of plasminogen to plasmin by binding to fibrin initiating fibrinolysis with limited systemic proteolysis. This can lead to degradation of fibrinogen in blood samples removed for analysis
Inform patients that bleeding can occur 1 or more days after administration of tnkase.
The drug is in the tissue plasminogen activator (tpa) class of medications. Tnk (tenecteplase) dissolves blood clots in certain blood vessels in your body Blood clots happen when your blood thickens. Tenecteplase is used in adults to treat a stroke caused by a clot (acute ischemic stroke) and to lower the risk of death from a certain type of heart attack
Tenecteplase may also be used for purposes not listed in this medication guide. Tenecteplase is an effective thrombolytic agent for eligible patients with stroke who are treated within 4.5 hours after the onset of stroke However, data regarding the effectiveness of. The original trial supports tnk as a safe, effective alternative to tpa for ais, reinforcing findings from other large trials
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