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We first review literature on sex differences and hormonal underpinnings of social behavior (section 2), with a focus on brain regions underlying regulation of key social cognitive skills, social recognition, social learning, as well as known sexual dimorphisms in social interactions and aggression. Biological and genetic differences in combination with environment and culture have resulted in the cognitive differences among males and females. Taken together, sexual differentiation is best studied in an integrative manner that considers the interaction of genetic, hormonal, and environmental factors acting at multiple sites through development to cause sex differences in neurobehavioral traits.

These findings uncover novel sex differences in neural projections of fear. Sex differences in cognition are widely studied in the current scientific literature We will begin this review by highlighting sex differences in neurobehavioral measures in adolescence that are linked to brain function

We will then summarize neuroimaging studies examining brain structure, connectivity and perfusion.

This chapter provides a developmental perspective to understanding neural and behavioral sex differences, focusing on cognition

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